SPRAVATO® Treatment
When nothing else has worked, you still have options. SPRAVATO® offers fast-acting relief for adults living with treatment-resistant depression or suicidal thoughts, bring hope when it matters most.
When You Need Help, Fast
Get Treatment That Doesn’t Make You Wait
SPRAVATO® (esketamine) is a fast-acting, FDA-approved nasal spray for adults with treatment-resistant depression or suicidal thoughts. Administered under medical supervision in our Oregon and Washington clinics, SPRAVATO® offers relief when other treatments have failed. It works differently from traditional antidepressants—often bringing results within hours or days instead of weeks.
What SPRAVATO® Can Treat
When You’re Ready, We’re Right Here
Whether you’ve been diagnosed or not, we help you understand what you’re feeling, and what to do next.
Benefits of
SPRAVATO®
Fast treatment for those who’ve tried everything else – FDA-approved SPRAVATO® treatment for adults in Oregon and Washington with treatment-resistant depression or suicidal thoughts.
Rapid relief for treatment-resistant major depression
FDA-approved for suicidal ideation
Administered in a calm and safe, supervised clinical setting
May reduce symptoms within hours or days
Covered by most insurance with prior authorization
For When the Darkness Won’t Lift
Is SPRAVATO® Right for You?
SPRAVATO® is designed for adults with major depressive disorder (MDD) who haven’t found relief from oral medications or who are experiencing suicidal thoughts.
If you’ve tried at least two antidepressants without success—or you’re in a mental health crisis and need help fast—SPRAVATO® could be a powerful next step. Our team will walk you through every part of the process.
"Great compassionate professional service. Wonderful atmosphere. The procedure is painless. For me it has been remarkable but i have to have it repeated every six months."
how it works
Your Path Forward Starts Here
Start with a free phone consultation
Talk with an intake coordinator who gathers your information and schedules you to meet with one of our providers.
Get a personalized care plan
Our providers tailor your treatment plan using real data, proven treatment methods, and your own lived experience.
Begin your path forward
You’ll move forward with services that meet your needs, and a team who’s with you.
All Locations
01
Active Path in Clackamas offers expert mental health care in Oregon including therapy, psychiatry, TMS, and SPRAVATO®, all located near Clackamas Town Center.
02
Active Path in NW Portland offers compassionate mental health care including talk therapy, psychiatry, TMS, and SPRAVATO® at Montgomery Park.
03
Active Path in Salem provides therapy, psychiatry, TMS, and SPRAVATO® services, all from our south Salem clinic for compassionate mental health care that’s close to home.
04
Active Path in Tigard offers talk therapy, psychiatry, TMS, and SPRAVATO® near I‑5 for convenient, compassionate mental health care in Tigard, Oregon.
05
Active Path Kirkland offers expert mental health care including therapy, psychiatry, TMS, and SPRAVATO® centrally located in Kirkland & Bellevue Washington, to help you heal near home.
06
Active Path Vancouver & Camas provides expert mental health services in Washington including therapy, psychiatry, TMS, and SPRAVATO® located at the Columbia Tech Center.
frequently Asked Questions
FAQs About SPRAVATO® Treatment
01 How is SPRAVATO® different from regular antidepressants?
SPRAVATO® acts on the NMDA receptors in the brain, targeting depression in a faster and different way than SSRIs or SNRIs.
02 Is SPRAVATO® safe?
Yes. SPRAVATO® is FDA-approved and administered only in certified clinics under medical supervision to ensure your safety and comfort.
03What are the possible side effects?
The most common side effects of SPRAVATO® when taken alongside an anti-depressant include:
- Feeling detached from yourself, your emotions, thoughts, and the environment around you
- Increased blood pressure
- Sleepiness (sedation)
- Slowed breathing
Side effects from SPRAVATO® typically occur shortly after taking the medication and wear off during treatment and throughout the day. Your healthcare provider will discuss side effects in more detail during your evaluation.
04 How soon will I feel better?
05 What is the treatment schedule like?
SPRAVATO® is typically administered twice weekly for four weeks, then once weekly for the next four weeks. After that, treatment is typically weekly or biweekly during the maintenance phase depending on the result.
06 Can I drive after treatment?
No. You’ll need someone to drive you home after each session, as side effects like drowsiness or dissociation are possible.
07Is it covered by insurance?
SPRAVATO® is covered by most insurance plans. Active Path Mental Health is in-network with most major commercial insurance plans.
08How is esketamine (SPRAVATO®) different from ketamine?
SPRAVATO® is derived from ketamine but they are not the same thing. Ketamine is composed of two molecules (also known as enantiomers) called esketamine and arketamine. Esketamine is considered the “more active” enantiomer that has a higher affinity for the target receptors in the brain that lead to an antidepressant effect.
09What conditions can SPRAVATO® treat?
- MDD
- MDSI- (Major Depression with Suicidal Ideation)
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When You're in Crisis, We’re in Reach
If depression or suicidal thoughts have you feeling stuck, SPRAVATO® could help. Reach out today because relief might be closer than you think.